Gene Machines - Kapanidis Group : All Pages

• Gene machines, one molecule at a time
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• Research interest
• 1a. Mechanisms of gene transcription Gene Machine: bacterial RNA polymerase; In vitro transcription studies
• 1b. Spatial organisation of transcription in vivo
• 2. Mechanisms of influenza virus replication and transcription Gene Machine: Influenza RNA polymerase
• 3. Mechanisms of DNA repair in bacteria
• 4. Mechanisms of DNA recombination Gene Machine: DNA recombinases
• 5. Biosensors for DNA, RNA and pathogen detection
• 6. Methods: single-molecule imaging and super-resolution microscopy
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• Single-molecule fluorescence spectroscopy
• Total Internal Reflection Fluorescence (TIRF) Microscopy
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• Antimicrobial resistance
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• Publications before 2015